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Communicable Diseases --- Virulence --- Bacterial Infections --- Bacteria --- diagnosis --- pathogenicity
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Substance abuse --- Medical screening. --- Communicable diseases --- Diagnosis. --- Diagnosis.
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Substance abuse --- Communicable diseases --- Addicts --- Treatment --- Diagnosis --- Diseases
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Xenografts --- Communicable diseases --- Government policy --- Prevention --- Government policy
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Communicable diseases. --- Public health surveillance. --- Epidemiology. --- United States. --- Management.
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Communicable diseases --- Communicable diseases. --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Medical microbiology --- Epidemics --- Quarantine
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Communicable diseases in animals --- -Livestock --- -Transboundary animal diseases --- -Prevention --- Diseases --- -Prevention --- Prevention
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Infection --- Communicable Diseases --- Communicable diseases --- Communicable Diseases. --- Infection. --- Maladies infectieuses --- Communicable diseases. --- Périodiques. --- Infectious Diseases --- Communicable Disease --- Disease, Communicable --- Disease, Infectious --- Diseases, Communicable --- Diseases, Infectious --- Infectious Disease --- Infectious diseases --- Contagion and contagious diseases --- Contagious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Infections --- Disease Outbreaks --- Disease Transmission, Infectious --- Diseases --- Medical microbiology --- Epidemics --- Quarantine --- Causes and theories of causation --- Infection and Infestation --- Infections and Infestations --- Infestation and Infection --- Infestations and Infections --- Infections. --- Maladies infectieuses. --- Periodicals.
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With one-third of the world's population infected with Mycobacterium tuberculosis, over two million people a year dying from tuberculosis, and the appearance of multidrug-resistant strains, the need to understand the biology of M. tuberculosis, and so to develop new interventions, has become acute. In Mycobacterium tuberculosis Protocols, leading investigators with extensive practical knowledge and experience describe their best methods for studying this dangerous pathogen. Packed with step-by-step instructions to ensure successful results, these methods range from basic handling techniques to the application of functional genomics. These molecular techniques are suitable for research in genetics, biochemistry, microbiology, cell biology, epidemiology, and diagnostics, and are at the forefront of biological research as a whole, as well as in focused M. tuberculosis research. Highlights include methods for the basic safety and culture of M. tuberculosis, fractionation of the bacterium (nucleic acids, lipids, culture filtrate, and capsule), the analysis of gene expression (start-site mapping, real-time PCR, microarrays, and proteomics), the growth of the bacterium in macrophages and low oxygen, cytological analysis of the bacteria, and diagnostics. Highly practical and accessible, Mycobacterium tuberculosis Protocols utilizes advanced functional genomics and mutagenesis methodologies to provide both experimental and clinical investigators all the powerful techniques needed to illuminate the molecular biology of tuberculosis and its interactions with host cells, and so drive work on the wide variety of emerging therapeutic opportunities.
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At a time of rising concern about drug resistance and falling output of new antibacterial compounds, antibiotic research has once again returned to the forefront of medical science. In Antibiotic Resistance: Methods and Protocols, Stephen Gillespie and a panel of leading clinical and diagnostic microbiologists describe a series of detailed molecular and physical methods designed to study the growing problem of antibiotic resistance, as well as facilitate new antibiotic research programs for its effective redress. The techniques range widely from those that provide rapid diagnosis via DNA amplification and phage display, to those for plotting the transmission of resistant organisms and investigating their epidemiology. The methods are readily adaptable to a wide range of resistant bacterial organisms. In order to ensure successful results, each method is described in minute detail and includes tips on avoiding pitfalls. Practical and wide-ranging, Antibiotic Resistance: Methods and Protocols provides a collection of indispensable techniques not only for illuminating the basic biology of antimicrobial resistance, but also for developing and implementing new diagnostic and epidemiological tools.
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